![]() Agent Cockpit application - a hybrid iOS/Android application for sales force the application was developed and deployed to all sales staff.The projects delivered for the team included: Working with vendor on specifying and accepting a delivery.Leading a development team on given project and developing desired functionalities.Analyzing business requirements to provide functional specification.Creating solution design for desired projects and programs, including detailed integration design including estimations and participating in vendor selection.Creating and updating a centralized architectural repository of Czech and Slovak market including enterprise and application architecture in Sparx EA.Working as a Solution Architect in Czech and Slovak Provident's IT Development team, I was responsible for delivering enterprise and application architecture as well as providing analytical and development delivery for selected projects. Agent Technology & Mobility - bringing market solution across the group to new markets, providing a common integration platform for mobile applications, developing a hybrid Android/iOS application for sales team.Strategic Digital Platform - introducing a new product concept for home credit, me and my team responsible for integration architecture, financial reporting, call-centre systems integration and bringing the legacy and digital systems to same level of features.The projects delivered or worked upon include: Leading an In-House development team using Kanban methodology, providing coaching to new members of the team and setting the development standards.Delivering Solution Concepts, estimations and integration architecture for group-wide and local projects and programs (see below).Managing Czech Provident application architecture, integration principles and common architecture repository.Working as a Czech market team leader of Solution Architecture & Development team in IT Delivery, I was responsible for a team of 3 solution architects and 4 developers (spanning internal employees and contractors) in following areas:
0 Comments
![]() Push/pull the book cart out of the alcove and across the room. ( screenshot)īUG NOTE: If you shoot the planks and then quit the game before actually picking up this silver reward, you may find you're unable to pick it up next time. Shoot the boards and squeeze in to get a silver reward (1/10). LIBRARY: Once inside, Lara looks to her right, alerting you to the boarded-up alcove. Enter and follow the corridor to another door. Return along the balcony to the library door. Return through the corridor to the balcony above the MAIN HALL. (For more info on outfits, see the Legend Rewards page.) The other alcove contains Lara's bed, behind which you'll find another bronze reward (3/16). Off to one side is a walk-in closet where you can change into any outfits you've unlocked so far. Go through the door there and follow the corridor to Lara's room.īEDROOM: Use the two dagger-like switches to open the Medusa-head plaque and take the PISTOLS. ![]() Follow the balcony to the other end (above the TECH ROOM). The first door off the balcony leads to the LIBRARY, but let's go get the pistols first. You'll have to do some climbing to get those. Note, however, that the grapple doesn't work on the bronze rewards in the alcoves in the gym (below). In some cases you'll need to use manual aim with the grapple. ![]() NOTE: You can use the grapple to grab this and other bronze rewards. Pull to open a secret compartment containing another bronze reward (2/16). Locate the round plaque with the telltale glint on the end wall and latch onto it with the magnetic grapple. When you reach the balcony, look to the right. ( screenshot)Ĭross the MAIN HALL and go upstairs and to the left. Use the laptop computer on the floor to open the safe and get the MAGNETIC GRAPPLE. ( screenshot) Cross the room to the glassed-in TECH ROOM where Zip is working. MAIN HALL & TECH ROOM: At the start, look to the left to find a bronze reward (1/16). Once you've finished here and have all the rewards, re-save and proceed with the main adventure. (If you're not sure what I mean, see the footnote at the bottom of this page.) Then, if you do encounter a bug, you can reload the backup save and try the Manor level again. I highly recommend setting aside a backup save file before starting to play Croft Manor. The Data section in the PDA shows the rewards you've found in each level, including Croft Manor.īUG NOTE: Several potential glitches may occur if you play part of this level, save rewards, quit the game and then come back to Croft Manor. The next time you enter Croft Manor, Lara will reappear at the starting position, but any rewards you've found should still be in your inventory. The rewards you've found in the manor will then be added to that save. Then select your current save file from the list. To do this, press Escape/Pause and choose 'Save Rewards' from the menu. Remember to SAVE REWARDS before quitting, though, so you won't have to get them again next time. I have not noted the locations of the CHECKPOINTS, since you cannot save manually in this level, and there are few places where Lara can die. If you get disoriented, the PDA includes a floor plan showing Lara's current location. So I have suggested a possible sequence here. The rewards can be retrieved in any order however, you do need certain equipment (grapple, guns, light) to obtain certain ones. The only goals are exploration and reward hunting. None of the items or rewards are in place, and none of the doors leading to other rooms (pool, library, etc.) will open. Before completing the Bolivia level, only the main hall of the mansion is accessible. GENERAL NOTES: Lara's home is accessed from the game's Main Menu. ![]() To Change the Default File Name for Screenshots However, the command appears only when you hold down the Option key while control-clicking. You’ll find the Copy as File Path command in the destination folder’s Control-click menu. You can either type the file path into Terminal, or drag and drop the relevant folder into Terminal to paste its file path.Īlternatively, you can also copy the file path and then paste it into Terminal. Replace with a new Finder save location that reads something like this: /Users//Pictures/Screenshots On macOS High Sierra and earlier, you need to rely on this Terminal command: defaults write location & killall SystemUIServer This shortcut turns the cursor into a crosshair you can then click and drag it across the part of the screen you want to capture. You’ll need to press Cmd + Shift + 4 if you want to take a screenshot of a particular portion of your Mac screen. Use a Snipping Tool to Screenshot Part of a Mac Window The screenshot will get saved as a PNG file. You can click on the image to edit it, or do nothing and let it auto-save to your desktop. When you do that, you’ll see an image appear in the bottom-right corner of your screen. Take a Screenshot of the Entire Screen on Your Macįor this, you need to press Cmd + Shift + 3. If the shortcuts methods below don’t work, ensure that you’ve enabled the feature from the System Preferences > Keyboard > Shortcuts > Screenshots. Keep in mind that these screenshot shortcuts work on every Mac model, so they’re how you take a screenshot on a MacBook Pro, a MacBook Air, or an iMac. We’ll go through your options one by one, as the best one to use depends on what exactly you want to take a screenshot of. You can choose from a variety of different keyboard shortcuts to screenshot your Mac. For further details, check out how to put the Mac screenshot in the clipboard.How to Take Screenshots on a Mac Using Keyboard Shortcuts What if you want the screenshot to be captured and stored in the clipboard? The simple solution is to include the Option key in the combination as in, Command + Option + Shift + 3. The three key combinations I mentioned above will save the screen capture as an image in the designated folder. Like I mentioned, the target window doesn’t need to be at the top as long as it is even slightly visible, take the cursor on it (the window will be highlighted) and click for a screenshot. I then take the cursor on the window of my choice and click on it. This turns the cursor to a small camera icon. Though not necessary, I keep the chosen window at the very top and then use the key combination – Command + Shift + 4 + spacebar. If you’re like me and are interested in only one window, there is an even better way to get the job done. Right-click to return to the normal mode, if you decide not to take a screenshot. ![]() These are the x and y co-ordinates of the screen. Also, when the cursor turns into crosshairs, you’ll notice a couple of numbers. When you release, a screenshot of the selected area will be taken and stored on the desktop (or the designated folder) as a png image file. Click and drag to select an area on the screen. To capture only a part of the screen on the Mac, use the key-combination Command + Shift + 4. However, there are smarter ways to get only a portion of the screen or a window of your choosing. If you want only a specific window or select an area, you can edit and crop the image. The above key combination – Command, Shift and 3 keys – captures the entire Mac screen. For step by step instructions, refer how to change the default location of screenshots on the Mac. You can change this with a couple of commands executed through the terminal window. Double click to open it in Preview.įYI, on the Mac, the Desktop is default location to which the screenshots are saved. The screenshot image is quite large – about 1MB – on my MacBook Pro. ![]() Hold Command + Shift + 3 to get a screenshot which is immediately saved on the desktop as a png image named “Screen Shot YYYY-MM-DD at HH.MM.SS am/pm” (On Mac OS X Yosemite and El Capitan). There are three key-combinations for taking a screenshot on the Mac: Key-combination Keyboard shortcuts for screen capture on the Mac ![]() Non-cross-resistance regimens are commonly used in the treatment of advanced breast cancer 6. Therefore, it remains controversial which chemotherapy regimen is superior and how many cycles of that regimen are appropriate for HR + /HER2-/LN+ patients. ![]() Hormone receptor-positive (HR + )/human epidermal growth factor receptor 2-negative (HER2-) breast cancer is known to be non-responsive to chemotherapy however, lymph node positivity (LN+ ) is an indicator for chemotherapy. The patients in the VbMF group had better survival outcomes. If the pathological response was poor, the patients were randomized to receive five cycles of CAVP or a combination of vincristine, bleomycin, methotrexate, and fluorouracil (VbMF). In their trial, all patients received three cycles of neoadjuvant CAVP. adapted this postoperative treatment strategy 5. Both trials failed to demonstrate a significant increase in the pCR rate after modification of treatment based on clinical response in patients who were non-responsive to NCT.Ĭompared to clinical response, administering additional treatments with different mechanisms based on pathological response may be a reasonable therapeutic approach. All responsive patients were randomized to receive four additional cycles of CAVP or docetaxel, whereas non-responsive patients received four cycles of docetaxel. 4 were administered NCT with four cycles of a combination of cyclophosphamide, doxorubicin, vincristine, and prednisone (CAVP), and clinical response was evaluated by physical examination after four cycles of NCT. All non-responsive patients were randomized to receive either four cycles of TAC or four cycles of vinorelbine plus capecitabine (NX) 3. The GeparTrio trial adjusted the NCT regimen based on ultrasound assessment after two cycles of a combination of docetaxel (Taxotere), doxorubicin hydrochloride (Adriamycin), and cyclophosphamide (TAC therapy). Two major RCTs have explored the advantages of altering ongoing NCT after an early assessment of the initial clinical response. Consequently, two strategies were established to overcome potential drug resistance the first was adding a new drug in the NCT setting to improve the pCR rate, and the second was adding a non-cross-resistant regimen in a selected population with a high recurrence risk (i.e., non-pCR patients). Although no survival benefit has been found with neoadjuvant chemotherapy (NCT), these trials have demonstrated that the pathological complete response (pCR) was associated with better survival. Previous randomized controlled trials (RCTs) have failed to illustrate a significant difference in survival outcomes between using the same chemotherapy regimen in neoadjuvant and adjuvant settings 1, 2. For patients non-responsive to neoadjuvant chemotherapy, adjuvant non-cross-resistant chemotherapy did not significantly improve distant disease-free survival compared to ET alone. Comparatively, the observation group showed a trend towards better distant disease-free survival. After a median follow-up period of 72.4 months, the 5-year distant disease-free survival was 92% and 90% in the chemotherapy plus ET and ET-alone groups, respectively. The final intention-to-treat analysis comprised 379 patients. Distant disease-free survival was the primary endpoint. Forty patients responsive to neoadjuvant chemotherapy and with Miller and Payne G4 or G5 and LN- status were assigned to the observation group. Patients received four cycles of non-cross-resistant adjuvant chemotherapy plus endocrine therapy (ET), or ET alone. There are few studies focus on post-neoadjuvant treatment in hormone receptor-positive (HR+)/human epidermal growth factor receptor 2-negative (HER2-)/lymph node-positive (LN+) breast cancer, a multi-center, open-label, randomized, controlled phase III trial was conducted to evaluate pathological response-guided non-cross-resistant adjuvant chemotherapy in patients with HR+/HER2-/LN+ breast cancer who were non-responsive to primary chemotherapy. ![]() Vibrating Cock Rings: ColorPoP Screaming O Vibrating RingĬock rings round out the wearable vibrator genre, partners with penises and without pleasure in equal measure.It also comes with two sets of settings - one that adjusts for intensity, and one that changes up the pulsing pattern - leaving you with plenty to explore. This bullet vibrator is small, subtle, and shaped for all kinds of different stimulation. Je Joue is a great option for those who love the idea of rabbit ears, but are a little intimidated by the size and intensity of a two-in-one toy. Bullet Vibrators: Je Joue Rabbit Bullet Vibe.(It comes personally recommended for beginners by Sammi Cole, Lovehoney’s in-house sexpert.) Small, slim, and incredibly strong, this toy is as discreet as it is powerful-and it’s very powerful. (Remember, it’s only a rabbit vibrator if it offers two-in-one stimulation, so any bullet with rabbit ears would still be classified as a bullet.)Ī bullet in its truest form, the Tracey Cox Supersex Bullet Vibrator is an excellent intro toy. They tend to have relatively smooth, round ends, but some boast tips that look like rabbit ears. Bullets are typically thinner and shorter than other vibrators (though some bullets are thicker than others). Bullet Vibrators: Tracey Cox Supersex Bullet Vibratorīullet vibrators are small, cylindrically shaped vibrators that typically resemble-you see where this is going-bullets.Please note that if you purchase something by clicking on a link within this story, we may receive a small commission of the sale.Ī version of this story was published October 2019. Tracy’s Dog is a SheKnows sponsor, however, all products in this article were independently selected by our editors. ![]() Our mission at SheKnows is to empower and inspire women, and we only feature products we think you’ll love as much as we do. And it’s really no problem if you find yourself in the latter category-after all, you can always buy more than one. There might be an obvious winner, or a few toys you’re tempted to try. From there, peruse the different types of vibrators to determine which toy genre best fits your wants and needs. To figure out which one to buy, take a moment to consider what kind of pleasure you enjoy, as well as what kind of play you’d be interested in exploring. There’s no one-size-fits-all beginner vibrator, because vibrators do all kinds of different things and all of our tastes are different. But for the most part, each genre offers a different experience. ![]() ![]() There’s a lot of variety within some of these categories and less within others. (Rather than what they aren’t.) Though there’s a range of toys on the market, shoppers can easily sort them into a handful of categories: classic penetrative vibrators, clitoral vibrators, rabbit vibrators, wand vibrators, bullet vibrators, finger vibrators, tongue vibrators, vibrating cock rings, and vibrating butt plugs. Now that we’ve gotten that common misconception out of the way, it’s time to focus on what the different kinds of vibrators are. While there’s a lot of overlap between the two categories, the words aren’t always interchangeable. And not all vibrators are dildos-in fact, a bunch of vibrators aren’t phallic or penetrative at all. Not all dildos are vibrators, because not all dildos vibrate. Though many of us use the term “vibrator” to describe any kind of penetrative sex toy, the label is best applied to toys that actually vibrate. ![]() Message the mods for flair Print SF Resources || SF Mags and Blogs | Free SF Books | Related Subreddits To conceal spoilers: >!No spaces around spoiled text!< Use common sense when reading about a book or author you don't wanted spoiled. Comments with spoilers will not be moderated, and hidden spoilers are discouraged in discussions about individual books. The cognitive slurry of generative AI adds no value and will be treated as spam. Users come here for the opinions of and discussion with other human beings. Polls are not allowed without prior permission from the moderators.Ħ: Tag digital book deals with and in post titleĮxample of an acceptable post title: Such-and-such book by so-and-so is $2.99! Text posts containing an image link must include a text explanation of the context around the image. This means no posting, linking, or recommending your own content, or any content produced by a person or company you're affiliated with. ![]() This includes, but is not limited to, hate speech and fighting about politics. All mod actions will be taken with these goals in mind. Our guidelines were designed to foster a diverse and welcoming discussion community while avoiding drama, flamewars, and promotional activity. Say "hi" at our sister subreddits- SpecArt and SF Videos-and join our reader-managed Goodreads group. The key is that it be speculative, not that it fit some arbitrary genre guidelines. History, Postmodern Lit., and more are all welcome here. Not sure what counts as speculative fiction? Then post it! Science Fiction, Fantasy, Alt. Canticle for Leibowitz Rendezvous with Rama Princess of Mars Altered Carbon Foundation Blindsight Accelerando Old Man's War Armor Cities in Flight A Brave New World Children of Dune Stranger in a Strange Land Dhalgren Enders Game Gateway A Fire Upon the Deep Neuromancer A Clockwork Orange Ringworld Diamond Age Lord of Light Hyperion Startide Rising Terminal World The Forever War Hitchhiker's Guide to the Galaxy The Hunger Games Left Hand of Darkness Man in the High Castle The Martian Chronicles The Player of Games The Shadow of the Torturer Sirens of Titan The Stars my Destination To Your Scattered Bodies GoĪ place to discuss published Speculative Fiction |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |